Regenerative Medicine 2023
Utilizing our body's natural powers
Definition: medicine focused on new treatments to heal tissues and organs, and restore function lost due to aging, disease, damage or defects.
The modalities of regenerative medicine take inspiration from endogenous compounds (chemicals originating within the body). The human body has a natural ability to heal itself in numerous ways.
“Nature is always more subtle, more intricate, more elegant than what we are able to imagine.” - Carl Sagan
I think this idea of viewing nature as the ultimate technology aligns with a lot of my beliefs in a variety of industries. I will be expanding upon this concept in upcoming posts about computing, manufacturing, agriculture, freshwater access, and more!
“Cartilage activated immune cells that target inflammation, combined with progenitor cells aid tissue regeneration…"
“…found to have the ability to reverse cartilage damage in the synovial membrane and diminish the inflammation as well.”
“…a protein called XIRP2, which has the ability to sense damage to the cores, which are made of a substance called actin. Shin and his team found that XIRP2 first senses damage, then migrates to the damage site and repairs the cores by filling in new actin.”
Stem Cell Therapies
“The Difference Between Getting Stem Cells Internationally Vs. The USA, Peptides, Testosterone & Hormones, Tissue Engineering, DNA Editing, Truths & Myths Of Regenerative Medicine & More With Dr. Adeel Khan.” (July 15, 2023)
^ in depth interview about stem cells and regenerative med
→ differentiates into specialized cells
→ unable to renew itself
Adipose Derived Stem Cells
Young vs Old stem cells
Umbilical Cord Stem Cells
What are exosomes? An extra-cellular vesicle that contains a multitude of compounds.
It appears that exosomes are a part of how stem cells work during differentiation.
The advantage this may have over stem cells is that it is not living matter. This eliminates the runaway risk of cancer where faulty DNA can cause tumors.
Cellular reprogramming is no longer a thing of science fiction. Soon we will have genetically modified humans ubiquitously walking amongst us.
Follistatin Gene Therapy
Longevity Gene Therapy
Gene Editing Vectors
Adeno-Associated Virus (AAV)
High Capacity Cytomegalovirus Vector
^ backed by Peter Thiel
3D Bioprinting/Organ Regeneration
A volunteer with severe liver disease will soon undergo a procedure that could lead them to grow a second liver.
Hormone Replacement Therapy
HRT for Women
An emerging exciting peptide that has a variety of amazing effects
Semax/Selank (Melanocortin receptors)
These peptides are commonly used as a nasal spray for brain health effects. It is even prescribed in Russia for post-concussion, stroke, and other brain damage
Semax Affects Resting Brain Structure
Semax in the Setting of Stroke
Semax and Gene Expression in the Brain
Semax and Cognitive Performance
Semax and Depression
Repaired brain chemistry changes after early SSRI exposure
Increases enkephalin (endogenous opioid) levels
Semaglutide (GLP-1 receptors)
There are even more therapies and longevity tech available nowadays. I will continue to observe evidence about which modalities are proving themselves to be effective. You can expect a lot more about this topic in the future!
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